Martin (John Amplas), a young man who looks around 20-years-old, boards a train in Indianapolis, Indiana for New York. At night, he breaks into a sleeping car and sedates a woman with a syringe full of narcotics. She struggles, but he tells her not to struggle or be upset because she wont feel pain. After a few minutes, the woman falls asleep, and Martin has sex with the unconscious woman. Afterwards, he slices her wrists with a razor blade so he can drink her blood. The woman bleeds to death in her sleep.
In the morning, the train stops in Pittsburgh, Pennsylvania where Martin disembarks. He is met by Tata Cuda (Lincoln Maazel) an elderly and hostile old man who claims to be his cousin from the Old World. Together, they travel by another train to the town of Braddock, a dying industrial suburb. They walk to Cuda's large house where he shows Martin his living quarters. Cuda then accuses Martin of being an 84-year-old vampire from his old country. He has taken in Martin because he is family, but tells him, "First I will save your soul. Then I shall destroy you." Martin denies being a vampire and implies that Cuda is merely his uncle rather than his cousin. Cuda then puts up strings of garlic on the doors to his and his granddaughter's room, and then holds up a small cross when Martin approaches him. Martin takes away the cross, and even takes a bite of the garlic mocking these attempts by saying bitterly, "There's no real magic... ever". Cuda tells Martin that he can come and go as he pleases. But he also warns Martin that he will kill him if he kills anyone in Braddock. He also tells Martin to stay away from his granddaughter Christine (Christine Forrest), whom arrives home from her job that evening.
Cuda introduces Christine to Martin, but also warns her to stay away from him. But Christine instead strikes up a friendship with Martin who confides in her about his vampire heritage. When Cuda later confirms Martin's claims to be a vampire, Christine, not surprisingly, refuses to believe either one. She thinks that Cuda and the other members of her family have driven Martin to insanity by making him think that he is a vampire. It is never revealed if Martin really is a vampire, or just a shy and lonely youth with troubled issues. Christine is the only person that Martin gets the courage to talk to. When Christine's boyfriend Arthur (Tom Savini) arrives at the house for dinner, Martin stops talking and backs away despite Arthur's attempt at a conversation. Christine later confides in Martin that she hopes to leave Braddock someday with Arthur, even though Martin points out that Arthur treats her badly and is both verbally and physically abusive towards her.
When Christine sees that Martin won't talk to anyone else, she buys him a phone which he installs in his room. Martin begins to repeatingly call a radio talk show where he describes what it's like to be a vampire. He becomes known on the radio as "the Count" to all the listeners. But the patronizing host (Michael Gornick) thinks he's just crazy.
Martin gets a job at Cuda's grocery store of stocking shelves, hauling boxes around, and even gets to be a delivery boy for some of the customers. One of his customers is a certain Abby Santini (Elyane Nadeau), who becomes taken in with Martin. She is a very friendly young woman who is depressed when she tells Martin that her husband is unfaithful. But Martin still does not have the nerve to talk with her, so she is happy to have someone to confide in with her life problems. Martin phones the radio show host to describe his infatuation with the housewife and senses that she wants to have sex with him. When the radio show host asks Martin if it is a sexual problem that he has involving women criticizing him during sex, Martin replies that he has never had sex with a woman who was awake.
One day, Martin travels by train to outside Braddock to look for victims. At a supermarket, he follows a young woman (Sarah Venable) home to her posh suburban house. He sees the woman's husband (Richard Rubenstein) leave for a long business trip, and Martin decides this would be the right time for more feeding. Martin returns to the house after dark and breaks in through the garage door. But it is Martin who gets the surprise when he bursts into her bedroom to find her in bed with her adulterous lover Lewis (Al Levitsky). After a vicious struggle, Martin jabs both of them with hyprodermic needles with narcotics, and waits for the drugs to take affect. He drags the unconscious body of Lewis from the house to a clump of trees across the street where he kills him by shoving a broken tree branch into his neck and drinks his blood. Martin returns to the house where he has sex with the unconscious woman. But out of compassion and pity, he decides to let her live.
Martin begins to have romantic monochrome visions of his vampire past (real or imagined), where he drained blood from a young woman and was chased through the streets of a nameless European town by a torch-lit mob.
During one Sunday at church, Cuda brings home Father Howard (George A. Romero) who asks him about the possibility of exorcism and demon possession. Father Howard calls upon the elderly Father Zulemans (Clifford Forrest, Jr.) over at Cuda's request. Together, Cuda and Zulemans confront Martin his bedroom and attempt to perform an exorcism on him. At this point, Martin remembers (another real or imaginary flashback), in the Old Country of people trying to perform an exorcism on him, and he flees them. Martin then flees from Cuda and Zuelmas as well. A little later that night, Martin terrorizes Cuda in a children's playground when he puts on a Dracula cape and puts false fangs into his mouth to pretend that he really is a vampire.
One day, Martin finally musters the courage to talk with Mrs. Santini during a routine delivery to her house where he tells her that he's aware of her attempts to seduce him and wants now to have sex with her. After having sex for the first time, Mrs. Santini becomes more depressed for she tells Martin that her husband just left her because she discovered that she cannot bear children, and that her desires towards him are based on sex and nothing else. But Martin wants to stay with her and help her move on with her life. Martin tells the radio show host about his affair with the housewife and that he no longer has the urge to attack other women.
Meanwhile, Arthur meets with Cuda and tells him that he wants Christine to leave town with him so they can get married and start a family. But Christine becomes angry at Cuda when he tells Arthur that insanity runs in their family and he shouldn't consider having children with her. Shortly afterwards, Christine packs up and leaves Braddock for New York with Arthur despite Martin telling her that Arthur is abusive towards her. But her mind is made up. Before leaving, Christine tells Martin that she really has no ill feelings towards him and just wants to make a fresh start with her life. She says goodbye to him and promises to write. But Martin knows that with an abusive and possessive man in Christine's life, she probably won't.
Depressed over losing his one true friend, Martin phones the radio show host and tells him that he's getting "shaky" and wants to go out looking for more victims. That night, Martin travels to a rough crime-ridden area of Pittsburgh and attacks two derelicts in a alley, injecting them with narcotics. He kills one of them by silting the bum's wrist and drinking his blood. Martin is about to kill the second one when a police car shows up and gives chase. Martin narrowly escapes during a long chase on foot which leads from the garbage strew streets and through a local store. Martin runs into an old warehouse where a drug deal is going down. A shootout between the two cops and the three thugs begins where all of them are killed, leaving Martin as the sole survivor who casually walks away from the carnage.
One day, Martin finds Mrs. Santini dead in her bathtub, after she had slit her writs with a razor blade. Martin anonymously calls the police to report the body and leaves. He phones the radio show host one final time to say that he really doesn't need friends or people to talk to for he is his own person. But when Cuda learns about Mrs. Santini's suicide, is mistakenly thinks Martin killed her and made it look like a suicide as he's done before. Cuda walks into Martin's room while he is asleep and kills him by hammering a wooden stake through Martin's heart.
Cuda buries Martin's body in his back garden, while over the closing credits various voices from people are heard talking to the radio show host asking the whereabouts of "the Count".
11.1 我现在在家看恐怖片好像吓不到了，但是我还是很喜欢看温子仁拍的电影，温子仁的运镜就真的非常温子仁。这一部居然出人意料的不是鬼片。Gabriel的movement，一动的多了动的快了，就不对了，就变成了Madison的了，有被笑到。
这很不温子仁 粗糙感如b级片质感的美恐 大内密探零零发恐成为最大剧透
片名那里有人翻译成“肿瘤侠”也是很有才华……三星半，不单纯血腥也不单纯悬疑，看到寄生加百列的那一刻还是有惊讶到
好家伙，这次主角真名就叫安娜贝尔！电锯惊魂配乐不知说好评还是出戏……背后倒爬感觉可以超越伽椰子的倒爬了，带劲！想起了《白发魔女》里的吴镇宇……
感觉制作很粗糙..少了一种质感. 特别是催眠那一段是我看过最简陋的太随意了。警局杀人那里倒是挺爽的，但是最后非常突兀的就结束了把科警察晾在一边就有点不明不白的。温子仁的作品不应该是这样的 说实话有点失望电影创意还是不错的如果能再打磨一下就好了。 6.5/10
再吐槽下这个片名翻译，「致命感应」很容易误导观众，以为是个灵异片。但是如果你去查一下 malignant 这个单词的意思的话，剧情走向其实已经有所暗示
同体共生的压迫与欺侮，是恶的释放，善的重生，还是自觉遵守的唯我意志与坏境消沉。当变化来临，禁锢的开始便是终结。在主题很好的情况下一定程度地限制了言说的结构与范围。所幸独立的视听风格与运镜技巧在呈现“现实”紧迫感的前提下，又极大了补足了剧作中闪失的疏漏与遗留。氛围的塑造依旧是导演的绝对武器。动作戏的部分尤让人爽利激涌。
温应该专门盖一个房子，以后拍片更加节省成本了
为了迁就午休时间，后期1.5倍速看完，但还是被屠杀那part惊艳到，手法太干净利落了，招招致命不需要补刀。
铅黄的用光和音效配现代戏居然丝滑又尖锐，风格化上不是往常的温子仁但做到了。黑暗的另一半的核，生出现实替换的构思很金。body-horror的巧思诡异中居然带着优美，背部逆行骨骼倒错，几场追逃戏居然跳出了舞步（不是哈哈哈）
血腥残暴版Frozen？这个剧本只看前十页是咋给green light的？先立项然后赶着拍赶着写？
没想到随便下了一部片子，居然是温神的电影。温神出品，必属精品。其实故事的结构也很简单，就是一个邪灵附身于女子身上作妖的故事。精彩点就是把一个老掉牙的故事拍的如此有惊悚感。从几桩死亡事件中，引出作案凶手的手法不一般。到死者身份的关联性，发现是多年前一起手术中的医疗人员。一点点把这个邪灵的真实特征身份给勾勒出来。当然其诡异的作案动作，很有日韩恐怖片中那些阿飘的风格，融入到了欧美恐怖片中。既有惊悚感又有悬疑性，恐怖场景的视觉冲击力也足够。
温子仁用实力证明你大爷还是你大爷，娴熟的运镜手法仿佛回到了电锯惊魂时期，结尾血洗警局那叫一个刺激，不过为什么肿瘤人就能把女主的身体秒变美国队长？
我缓缓打出一个问号，这配乐和音效是认真的吗。追逐戏里的警察仿佛里昂附身，加上挺多场景都有re的痕迹，既然如此不如设定再大胆一点，但结尾又耍回温情加悬疑。温子仁就是自己玩爽了，但从视效到故事都让人失望，连以前能把人吓尿的镜头都抛弃了。
大面积都是恐怖片常规惊吓段落，温子仁拍这种成色的片子想必是手到擒来吧。一直等到大梗揭晓，高概念和视听设计才终于完成高度适配，打开类型片观众期待的感官愉悦，但整个故事最后也并未挖掘到足够震悚的人性深度。P.S.爱奇艺剪掉的几段血腥杀戮戏都是精华。
对比温子仁前几部的作品，缺少了标志性恐怖的招牌，举例来说就是恐怖修女乍现时那种心提到嗓子眼的效果。不过整体还算不错。
太垮了，好好打磨一下做成超级英雄片倒是可以，XX侠什么玩意的？
温子仁玩得还是牛逼，这种寄生案例在医学史上层出不穷，作为影史却第一次呈现这么成熟。
和潜伏比确实是差一点，但就是不一样的方向，也还好啦。
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